Indocyanine Green for Injection, USP
Seaford’s Indocyanine Green for Injection USP is the leading fluorescence product trusted by physicians, to visualize fluorescence and guide their procedures. Indocyanine Green (ICG) is the gold standard in diagnosing several serious conditions and is a key diagnostic tool used by physicians worldwide.
INDOCYANINE GREEN FOR INJECTION USP A TRICARBOCYANINE DYE, IS INDICATED FOR3:
FOR DETERMINING CARDIAC OUTPUT, HEPATIC FUNCTION AND LIVER BLOOD FLOW.
FOR OPHTHALMIC ANGIOGRAPHY.
INDOCYANINE GREEN FOR INJECTION USP (ICG)2,4
The retention of Seaford’s ICG in the fenestrated choroidal circulation, combined with its low permeability,makes ICG angiography ideal for viewing the choroidal blood vessels.
Once injected, Indocyanine Green for Injection, USP, binds to plasma proteins and quickly circulates to the choroid layer, delineating the choroidal veins within 15-20 secs.
Indocyanine Green for Injection, USP, is cleared exclusively through the liver and then excreted through the bile. It does not undergo metabolism.
Indocyanine Green for Injection, USP, has an excellent safety profile, and adverse reactions occur very rarely (<1/10,000).
Using ICGA at initial presentation helps identify disorders of the choroidal circulation, allowing differential treatment approaches that may improve outcomes and safety for patients.
Key Features
Well tolerated1
Excellent safety profile1
The biological half-life of 2.5 to 3 minutes2
Rapidly bound to plasma protein2
Secreted entirely into the bile2
Cleared exclusively through the liver2
Peak spectral absorption at 800 nm2
Undergoes no significant extrahepatic or syndromes enterohepatic circulation2
Seaford’s indocyanine green for injection USP (icg) Specifications:
| PRODUCT | Indocyanine Green for Injection USP |
|---|---|
| PACK SIZE | Box of 6 vials of 25 mg of Indocyanine Green Powder for Injection, USP |
| MEDICINAL INGREDIENT |
Each Vial contains sterile, lyophilized green powder containing 25 mg lndocyanine Green for Injection, USP |
| DIN | 02485796 |
| PRODUCT CODE | PICG0025CA |
| EXPIRY | 48 MONTHS |
| AVAILIBILITY | Order from McKesson or Seaford Pharmaceuticals Inc. No minimum orders required |
References
1.https://radiologykey.com/clinical-applications-of-diagnostic-indocyanine green-angiography/
2.Indocyanine Green for injection, USP Product Monograph.
3.Use of diagnostic green’s verdye (ICG) in ophthalmology. (2020, September 01). Retrieved July 15,2022,
4.Indocyanine Green for Injection, USP Ophthalmology Focus – Diagnostic Green. (2020). Retrieved July 15, 2022,
